When both monitors are connected to the same GPU, PD behaves as expected: The logos on the About screen match the GPU and the hardware producing options for that GPU are available.
However, if I have one monitor connected to each GPU, PD cannot accurately determine which GPU to use and displays incorrect logo information when compared to the producing options.
In each of these screenshots, I show how Win10 lists my monitors and note which GPU is active. I combine that with PD's About screen and the available producing options. The monitor that PD is displayed on is shown in blue, and sometimes there is a 3rd (virtual) monitor that Windows created but that I've disabled.
The first image is when both monitors are connected to the Intel iGPU, and everything works as expected:

The second image is with both monitors connected to the nVidia GPU, and everything here is normal as well:

The problems start when the monitors are connected to different GPUs. Here PD detects the nVidia card but shows Quick Sync for producing. Win10 shows no extra virtual monitor:

The final configuration is the worst, with opposite information on the About and Produce windows and the hardware produce option completely unavailable. There is also a virtual monitor that requires an out-of-sequence monitor order:

Of the 4 combinations, 3 show nVidia hardware on the About screen but 3 show Quick Sync on the Produce screen (only 2 are viable).
All of these are with the Win10 Graphics performance preference tool (to select high power and low power GPUs by app) unchanged from the default of no apps selected - this is only what happens when the monitors are connected to different GPU ports.
YouTube/optodata
DS365 | Win11 Pro | Ryzen 9 3950X | RTX 4070 Ti | 32GB RAM | 10TB SSDs | 5K+4K HDR monitors
Canon Vixia GX10 (4K 60p) | HF G30 (HD 60p) | Yi Action+ 4K | 360Fly 4K 360°