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Make some free space on your "c" drive. You don;t have enough. The program requires a lot of free space on "c" even if it is installed on your other drive and even if all of your assets are on the other drive.
Also there are a lot of errors related to "DllHost.exe" Google for it and get rid of it if possible. Look at the last section of the dxdiag.exe file.
Thanks, I moved my cloud drive space to an alternate drive, which freed up about 80Gb on my C drive, cleared up the errors, uninstalled and reinstalled PD15, and reverted my video drivers to a previous version... that the last one was the thing that finally fixed it. Could have been a combination of things, but after the driver change, it started working.
You got me started down the right path - thank you very much!