NVIDIA has now released their Geforce 382.19 HotFix driver,which fixes stutter issues that are present in Prey with select hardeware configurations.
After this HotFix my Timline is runing 100%
Paul Pauls PC
X399 AORUS Extreme/AMD Ryzen2970WX/1xQuatro 4000 Driver:Geforce 419.67Skill V DDR4 64GB/3200MHz/Win10 prox64
Intel SSD 750/400 / Intel SSD 750/1.2Tb 1x4TB SSHD /1xSeagate 10TB pro
1xSamsung UA28D590 4k LUMIX GH5 1xLG HDR