Dan:
I can't speak with any authority, but I did a clean install of Windows 10 in early December. I reloaded my PD12 and it initially appeared to be working just fine. A couple of weeks later, I went to do some editing, and it wouldn't launch: the dreaded "pdr.exe" has stopped working message.
I upgraded to PD14 and all is well. I don't know whether PD12 got clobbered by a Windows 10 update or what ...?
I did read here on these Forums in the past of folks successfully using PD12 and Windows 10. It didn't work out for me, but there is no harm in trying to install PD12 on a Windows 10 computer. One trick I did not try was to see if I could get PD12 to work in "compatibility mode." I was on the brink of upgrading to PD14 anyways, so I did not pursue any options to try to get my PD12 to work on my Windows 10 computer.
Just my experience, for what it is worth. Have a great day.
Regards
-Phil
Windows 10 Pro x64
Dell XPS 8930
Intel CoreT i7 (4.6 GHz)
32 GB DDR4-2666 RAM
1 TB PCIe -x4 SSD
NVIDIA GeForce RTX 2060
PD14 Ultimate x64, 4207
CD4 Ultra and AD6 Ultra
Bleeping Computer Malware Response Instructor